Alternative Names biopsy, bone, bone lesion biopsy
Definition In this test, a piece of bone is removed for testing in the laboratory. A bone lesion biopsy is taken when osteomyelitis, rickets, or bone cancer is suspected.
How is the test performed? A bone lesion biopsy may be taken during surgery with the person under general anaesthesia. Or, it may be taken with the person under local anaesthesia. When a biopsy is taken during surgery, the surgeon cuts through the skin and removes a small sample of bone. When a biopsy is taken under local anaesthesia, a hollow needle is inserted into the bone. The needle with the bone sample is removed. The bone samples are then sent to the laboratory for testing. Pressure is applied to the site until bleeding stops.
What is involved in preparation for the test? A person should receive specific instructions from his or her doctor.
What do the test results mean? Normal bone appears as dense, compact bone as found on the outside of the long bones in the arms and legs. Normal bone also appears spongy and porous. This type of bone is found in the centre of long bones.
Abnormal bone may result from:
a non-cancerous (benign) bone tumour
a cancerous (malignant) bone tumour
a softening of the bones caused by a deficiency of vitamin D (osteomalacia)
a softening of the bones caused by an overactive parathyroid gland (osteitis fibrosa)
inflammation of the bone (osteitis)
Benign (non-cancerous) tumours include the following:
osteoid osteoma
osteoblastoma
bone cyst
fibroma
Malignant (cancerous) tumours include the following:
multiple myeloma
osteosarcoma
Ewing's sarcoma
Author: Reviewer: HealthAnswers Australia Medical Review Panel Editor: Dr David Taylor, Chief Medical Officer HealthAnswers Australia Last Updated: 1/10/2001 Contributors Potential conflict of interest information for reviewers available on request
